Brent W. Osborne, PhD


As a Consultant with Defined Health, Brent participates in opportunity assessments, indication prioritization/sequencing, search, and strategy projects. Brent regularly contributes to projects in the cardiovascular, CNS, ophthalmology, dermatology, and AIID spaces.

Before joining Defined Health, Brent was a postdoctoral fellow in the Wu Center for Molecular Cardiology at Columbia University. As a postdoc at Columbia, Brent studied the molecular mechanisms of smooth muscle function, which led to the development of two novel mouse models of hypertension. In parallel to his time at Columbia, Brent worked as an analyst for The Solution Lab (TSL), a non-profit life sciences consulting firm in NYC. During his tenure with TSL, Brent advised clients in both pharma and biotech firms develop business strategies through competitive intelligence and quantitative analyses of niche markets.

Brent earned a PhD in Cell and Molecular Biology from the University of Vermont, in Burlington, VT, where his thesis focused on structure-function relationships of novel modulators of protein kinase activity. Brent also earned a BSc from UVM in Biological Sciences where he studied the mechanisms of microbial pathogenesis. Brent has published in peer-reviewed journals, presented his work at national and international scientific meetings and is co-inventor on a patent originating from his graduate studies.